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Caspase cleavage of transcription factor Sp1 enhances apoptosis
Major hallmarks often observed in early AMD are thickening of the Bruchs membrane, reduced choroidal blood flow, and the appearance of drusen, deposits of metabolic products accumulating between the RPE and Bruchs membrane [6, 8,9,10]
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During an AJPH press briefing on Tuesday, Cindy Leung, a public health nutrition professor at Harvard, said people whose diet contained high quantities of UPFs had a 58% higher risk of developing dementia, a 46% higher risk of developing mild cognitive impairment, and a 47% higher risk of either of those two outcomes
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