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General guidelines: Heavy smokers (20+ per day): Match your tobacco habit in the first 12 weeks, then gradually reduce Moderate smokers (1015 per day): Start at your current consumption level and step down weekly Light smokers (under 10 per day): Match your consumption

It can linger for several days or even weeks if not properly addressed.

Case 1 The patient was a 13-year-old boy who was born to consanguineous parents and was seen for fragility of the skin and mucous membranes that began at age 5 years with small erosions that formed on the hands and feet after minimal trauma, pain and bleeding of the gums, diarrhea, and intermittent constipation