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In a randomized crossover trial comparing healthy subjects who smoked tobacco (maximum of 10 cigarettes per month), the acute use of nicotine-containing e-cigarettes significantly increased levels of circulating endothelial progenitor cells (flow cytometry) to the same magnitude as after smoking a traditional cigarette (41)

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Pixabay During follow-up 10 years later, investigators found smokers who puffed one cigarette or less per day increased their risk of lung cancer by nine percent compared to never smokers

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