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29 October 1994

It is recommended that patients use the nicotine dose of the inhaler completely and take doses more often during initial therapy to help control tobacco cravings

In the aforementioned study exposing human gingival fibroblasts to CS condensate or to nicotine-rich or nicotine-free e-vapour condensates [29], the detrimental effects were greater in cells exposed to nicotine-rich condensate than to nicotine-free condensate, suggesting that the possible injurious effects of nicotine should be considered when purchasing e-refills

In addition, cigarette filters are made with a plastic material called cellulose acetate, which does not biodegrade