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Clofazimine is at least partially metabolised in the liver via CYP3A4 and CYP1A2, thereby TB smokers may experience increased metabolite synthesis, potentially necessitating dosage adjustments

In practice, cigarette butts tossed on streets and beaches do not biodegrade

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"We are still looking into why that is." It also is well known that people who start smoking while they are still teenagers are more likely to be heavy smokers as adults