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It is sundried tobacco leaves of plant Nicotiana rustica and sodium bicarbonate (locally known as natron).[30,31] TERMINOLOGIES ASSOCIATED WITH HABITS WHICH INCLUDE TOBACCO AS WELL AS ARECA NUT, MAINLY PAAN ANDQUID Paan In India, the term paanrefer to the betel leaf itself [Figure 9].[8] Although paan is generally used to refer to the leaves of the betel vine, the common use of this word refers mostly to the chewing mixture wrapped in betel leaves.[32] Thus, the habit of chewing the quid is often colloquially described as paan chewing.[8] Thus, the word paan is from Hindi and Urdu

Some individuals might be more susceptible to this based on their genetics

That's too much