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Until now, there has been scant longitudinal data in large high-quality datasets linking exclusive e-cigarettes use to new-onset cardiometabolic health conditions, says Michael Blaha, M.D., M.P.H., senior author of the study and professor of cardiology and epidemiology at the Johns Hopkins University School of Medicine

PCA not only reduces the complexity of the data but also enhances the models generalization ability by mitigating the interference of redundant or noisy high-dimensional features

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