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Relative to bacteria in tobaccos, the difference of the distributions of the surface and endophytic fungi of tobacco leaves was less significant, indicating that the endophytic fungal communities of tobaccos were more abundant 30

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Carbohydrate metabolism and xylene degradation were positively correlated with Streptococcus , Staphylococcus , and Agrococcus that were differentially abundant in healthy oral microbiome, whereas strong negative correlation was observed with Prevotella , Capnocytophaga , and Eikenella that were differentially abundant in OSCC and smokeless-tobacco-consuming healthy samples

Progress was made in the late 1970s with the smoking rate falling to 36 percent in 1977