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Overdose poses risks for: Water intoxication (acute hyponatremia) Cerebral edema Acute confusion acute psychosis Heart arrhythmias Myoclonic seizures Hyperthermia (fever) Serotonin syndrome Liver failure Kidney failure Heatstroke, rhabdomyolysis, and serotonin syndrome are particularly likely to occur after ingesting various synthetic cathinones or phenethylamines combined with prolonged dancing, exposure to hot environments, and poor hydration