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PMIs challenge will be balancing mass appeal with the kind of discretion and accessibility that has fueled ZYNs rise.

Physicians provide brief counseling backed by the CDC and connect patients with nicotinereplacement options, prescription medications, and free resources such as Smokefree.gov or the national quitline at 1800QUITNOW

Some of these analogies were disseminated through an industry-funded proxy called Associates for Research in the Science of Enjoyment (ARISE), according to a 2007 study published in the European Journal of Public Health by tobacco researcher Elizabeth Smith

Others impose a tax on the amount of vaping liquid sold ( specific tax ), ranging from $0.05 per ml to $1.20 per ml (Chicago)