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In addition cigarette smoke exposure can make some strains of Staphylococcus aureus a microbe present in 30-60% of the global population and responsible for many diseases, some fatal more invasive and persistent, although the effect is not universal across all strains tested

1 2 "Leah Remini Subpoenaed to Testify in Harassment Suit Against Church of Scientology", ABC News, October 4, 2013

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When smokers have not gone for a smoke, it makes them irritable and anxious. While cigarettes are made of several substances, nicotine is the main ingredient drug in tobacco that triggers a release of chemicals in the brain