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As a result, EU disposables tend to have smaller tank capacities but higher nicotine concentrations

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In a statement to Reuters, the agency said it was investigating whether certain brands are being improperly sold without FDA approval and that it "plans to take additional action on this front very soon." The agency said it would focus on products with high-nicotine concentrations and flavors appearing to target young people, and take "swift action wherever appropriate." The FDA set the August 2016 deadline to rein in the fast-growing industry but allowed sales of Juul and other older devices to continue without regulatory approval until 2022

Also not included above are costs from smokeless or spit tobacco use, adult secondhand smoke exposure, or pipe/cigar smoking