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Oz argued for rescheduling as Schedule II, Smith and others said

When I first started to use e cigarettes I just wanted a good tobacco e juice flavour and wasnt too bothered or interested in all the other flavours I saw brands offering

These strong policies encouraged people to quit smoking and kept kids from starting. But rates of vape usage have gone up, along with the economic value of electronic cigarettes

For example, individuals experiencing anhedonia (whether as part of drug addiction or due to some other disorder like depression) display decreased activity in the ventral striatum, orbitofrontal cortex, and prefrontal cortex, as well as various abnormalities in dopamine signaling