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Increased DNA damage and cellular senescence may contribute to accelerated lung aging and COPD pathogenesis [53]

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Persistent or unexplained changes in smell or tasteparticularly when accompanied by fatigue, neurological symptoms, joint pain, or a history of tick exposureshould prompt a comprehensive medical evaluation

Frank Zappa Musician Composer Band Birth Date: December 21, 1940 Death Date: December 4, 1993 52 years old Birth Place: Baltimore, Maryland Children: Dweezil Zappa, Ahmet Zappa, Moon Unit Zappa As a singer, songwriter, rock guitarist, classical composter, recording producer and even occasional film director, Frank Zappa was as difficult to describe as his eclectic music was throughout his 30-year career