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Assuming a 30% prevalence of respiratory symptoms among the general population 27 , after applying continuity correction, the study required a total sample size of 426 to achieve a power of 80% for detecting an odds ratio of 1.8 11 at a two-sided p-value of 0.05

This collection of interviews between 1935 and 1969 traces the complicated trajectory of her star

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Therefore, to ensure that the increased toxicity of hP301L was not simply an effect of greater expression level compared to hTau, we assessed tau expression levels in all captured cells at 24 and 48 h, by measuring the intensity of V5 staining (Fig EV3D and E)