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128, 129 Finally, isoprostanes are stable metabolites resulting from the oxidative transformation of arachidonic acid metabolites and known biomarkers for oxidative stress in lung inflammatory diseases, such as asthma and COPD

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"These changes affect many of our colleagues, and we are focused on supporting them through this transition with care and respect, as we position the business for the future." In response to today's news, the company's share price dropped 1.6 per cent in early morning trading