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For example, smoking can damage the airways and alveoli (small air sacs) thereby causing lung damage, according to a fact sheet on the health effects of cigarette smoking from the CDC

1 2 3 "Rules and Regulations Implementing Republic Act 9211, Otherwise Known as the Tobacco Regulation Act of 2003" (PDF)

15 Large human immune profiling studies show that smoking affects both innate and adaptive immune responses, and some adaptive immune changes can remain even after smoking cessation, which suggests a lasting immunological effect

If you dont smoke cigarettes, you have to deal with withdrawal symptoms, which include trouble sleeping, feeling irritable or on edge, having trouble thinking and concentrating, feeling restless and jumpy, feeling down or sad, and feeling hungry