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Oxidative stress damages DNA by producing peroxynitrite (ONOO ) from the reaction of superoxide anions and nitric oxide 14 and correlates with increased airway epithelial cell apoptosis, pro-inflammatory signaling and DNA oxidation 15

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16 years, and in that time, the states health care impact is now estimated to be $3.2 billion a year. If HB 2382 is approved, the revenue gained from the tax would be directed toward funding public health programs, enforcing taxes on cigarettes, tobacco, and vapor products, and addressing the states current general fund shortfall

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