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The physical workload of the circulatory system contributes to increase blood pressure and lead to compound it with heart disease

According to the Surgeon Generals report on the effects of smoking on reproductive health, smoking can damage the genetic material in eggs and sperm, which can lead to higher rates of miscarriage, ectopic pregnancy, preterm labor, and birth defects

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The Cochrane authors found that using a nicotine patch and another type of NRT (such as gum or a lozenge) at the same time made it more likely that a person would successfully stop smoking than if they used one type of NRT alone