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Prolonged usage of nicotine gum without the intention to quit smoking may lead to various health-related issues in the long run, including: Seizure Sleep deprivation Premature hair loss Increased risk of oral cancer Nicotine addiction Nicotine gum is available in two doses: 2 mg and 4 mg

Retrieved February 20, 2022

The American Cancer Society's Cancer Prevention Study II found elevated relative risks (i.e., the risk of the conditions among smokers compared to nonsmokers) for current smoking of 10.9 for males and 5.1 for females for lip, oral cavity, and pharyngeal cancers (i.e., male smokers have 10.9 times higher risk of developing these cancers than male nonsmokers, and female smokers have 5.1 times higher risk of developing these cancers than female nonsmokers) and 14.6 for males and 13.0 for females for laryngeal cancer (Ref

Variation by baseline HDL-C was significant (p=0.03), but due to smaller changes in the studies where baseline HDL-C was unavailable, rather than to variation between the tertiles