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To think that in 1854, fully 40 years before Robert Koch discovered the bacterium that causes cholera, a lone London obstetrician named John Snow identified the source of a cholera outbreak with pencil, paper, and shoe leather

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Another form is pustular psoriasis, characterized by numerous pustular lesions filled with pus (202)

Of each PCLS, three independent locations were recorded generating 30-m-thick 3D stacks (10 , excitation wavelength 488 nm and 543 nm, emission filters BP 505550 nm and LP 560 nm)