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Given that SHGB levels decreased in the study after quitting smoking, this may be why testosterone levels fluctuate in some people before and after nicotine use

Acknowledgments The authors express gratitude to the NGS facility and Mass facility at IISER Bhopal for facilitating the sequencing and mass spectrometry experiments

This modulation helps reduce systemic inflammatory responses, which is why nicotine has become a topic of interest in studies involving autoimmune and inflammatory conditions

Full detox from nicotine is achieved within 4 to 6 weeks, after which many former smokers report a marked decrease in cravings and a substantial improvement in overall well-being