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Subjects were randomized 3:1 to CHANTIX 1 mg twice daily (N=486) or placebo (N=165) for 12 weeks of treatment and followed for another 12 weeks post-treatment

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Also, hyperlipidemic environments and oxidized LDL, conditions found in MS patients, induce phosphatidylserine externalization, caspase 3 activation, and platelet aggregation (162)