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Metabolite set enrichment analysis (MSEA) was performed on the web platform ( by inputting KEGG IDs

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The United States Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC) found that 1.63 million middle and high school students in the United States used e-cigarettes in 2024, which is 0.5 million fewer than the 2.13 million who used them in 2023