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Currently, the risk factors for hyperuricemia that have been identified are gender (male), increasing age, elevated body mass index (BMI), excessive purine dietary intake, alcohol consumption, fructose intake, and so on 5

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39 Studies have also shown levels of 4-aminobiphenyl-DNA adducts 40 and polycyclic aromatic hydrocarbon-DNA adducts 41 are increased in HCC tissue compared to normal liver tissue, suggesting that these tobacco carcinogens could play a role in HCC development

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