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Previous studies demonstrated that smoking is strongly associated accelerated ageing indices such as the Frailty Index 15 and mortality risk 16

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Japan Tobacco CEO Mitsuomi Koizumi told an earnings briefing in February: "We have very high expectations for growth of the so-called tobacco vapour category in five years or so from now." The iQOS is a tobacco stick that is heated just enough to produce an aerosol but not combust