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19 MRI processing To determine local cortical thickness measurements for each subject, the T 1 -weighted volume scans were processed using the automated CIVET pipeline (version 1.1.12) developed at the Montreal Neurological Institute ( For details regarding CIVET processing steps, see section 3 of Supplementary Information

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Long-term exposure to cigarette smoke significantly increases the risk of a variety of diseases, including chronic obstructive pulmonary disease (COPD) and lung cancer