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Methods: Sprague-Dawley rats were randomly assigned to five experimental groups: a control group exposed only to standard room air, a cigarette smoke exposed group treated with saline vehicle, two cigarette smoke exposed groups treated with acetylsalicylic acid (ASA) (15 mg/kg and 30 mg/kg, respectively), and a group treated only with ASA (30 mg/kg)

Our clinical research program examines the effect of the JUUL2 System on adults who smoke including the rate and level of nicotine absorption in the body and changes in exposure to tobacco-related harmful and potentially harmful constituents among adults who switch completely from smoking cigarettes to use of JUUL2 products, such as: Pharmacokinetic Studies: Pharmacokinetic studies assess the rate and level of nicotine absorption in the body as well as subjective effects of use of various products

Nicotine is the primary substance in cigarettes, other tobacco forms and vaping that make them addictive