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Based on animal experiments and human cell studies, a research group led by Alex Carll, professor of physiology at the University of Louisville School of Medicine in the United States, has for the first time identified that synthetic cooling additives commonly added to e-cigarettes can induce cardiac arrhythmias

This was evident from the significant drop in TER, increased IL-8 secretion along with enhanced cytotoxic reactiveness in TC culture models compared to the DC culture model (Fig

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