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In contrast to biomarkers of exposure (BoEs) that reflect exposure to certain substances, chemicals or products, BoPHs are biological indicators that reflect early changes in health status caused by exposure to harmful substances (e.g., tobacco smoking) and are used to evaluate the risk of developing disease before clinical symptoms appear

Smoking or passive smoking by the mother can cause: Nicotine and other chemicals in breast milk

The North American colonies were among the earliest governments to issue paper currency, as no European nation had authorized its use on such a vast scale

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