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Initially, the cross-sectional design precludes the establishment of causality between the use of nicotine pouches and the observed outcomes, thereby restricting the study to associations rather than definitive conclusions

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Differences in the Way Men and Women React to Smoking Professor Comasco continued, This discovery leads us to believe that nicotines effect on estrogen production has a significant impact on the brain, but perhaps also on other functions, such as the reproductive system we dont know that yet

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