To put it more succinctly, look to Glantzs paper from last December: Using e-cigs increases exposure to toxic chemicals for most users
As a direct consequence of a reduction in exposure to carcinogenic toxicants, switching to a cMRTP use should also lead to a significant reduction in urinary genotoxicity (a biomarker of total genotoxic exposure) compared with continued smoking and approach the urinary genotoxicity observed upon smoking abstinence [37]
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In case higher age contributes to elevated eCO levels, it could probably explain lower median eCO levels among these patients compared to those who reported smoking, as well as contribute to higher blood pressure in this group and more advanced coronary artery disease resulting in greater proportion patients presenting with MI as an index event
