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Recessive mutations in genes coding for enzymes of the kynurenine pathway namely kynureninase and 3-hydroxyanthranilic-acid 3,4-dioxygenase lead to combined vertebral, anal, cardiac, tracheo-esophageal, renal, and limb (VACTERL) congenital malformations (76)

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In a wide-ranging interview in Colorado, where some of the family lives, Good's parents and two of her brothers, Brent and Luke Ganger, talked to the AP about the joy Good found in life, their grief at losing her and their hopes that her death can bring some sort of change in a deeply polarized nation