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According to King's American dispensatory (a book first published in 1854 that covers the uses of herbs used in American medical practice), "upon the upper portion of the respiratory tract its influence is pronounced." Mullein was prescribed by Eclectic Physicians (a branch of American medicine popular in the 1800-early 1900's which made use of botanical remedies) who considered it to be an effective demulcent and diuretic, and a mild nervine "favoring sleep." Precautions Small hairs on mullein leaf may cause mechanical irritation in the mouth and throat if not filtered out of extracts prior to consumption

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Effectiveness - The packaging utilizes eco-friendly inks, recyclable paper substrates, and energy-efficient printing techniques, significantly reducing its environmental footprint

Notably, the reverse was not truestudents who said they smoked cigarettes were no more likely to report use of e-cigarettes when asked approximately 6 months later