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In the prospective (SECA-II) study, patients with unresectable CLRM were selected for LT if they met prespecified inclusion criteria, including resection of primary colon cancer, no evidence of extrahepatic disease, and response to first line chemotherapy, Overall survival of the 15 patients who underwent transplant at 1, 3, and 5 years were 100%, 83%, and 83%, respectively with a median follow-up of 36 months