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A 2015 study published in the Canadian Journal of Respiratory Therapy stated, Vaporization of cannabis is likely less harmful than smoking and Vaporizers show promise for cannabis users who want to avoid pulmonary problems and prefer a more rapid onset than edibles provide. However, the study also cautioned, Researchers have yet to gather some of the most necessary data regarding the topic. There have been no published randomized clinical trials investigating vaporization with long-term follow-up, the study concluded

In 2015, a minimum age of sale for e-cigarettes of 18 was introduced, making it illegal to sell e-cigarettes containing nicotine to under 18s or to purchase them on behalf of under 18s.[24] From 20th May 2016, a regulatory framework for e-cigarettes was introduced in the UK under the EU Tobacco Products Directive (TPD) Article 20.14 The regulations are due to be updated and strengthened following a review in 2023, but the timescale and content of the revised regulations has still to be decided at time of publication of this factsheet