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Nicotine enhances the breakdown of fatty acids and increases their content in the blood, which entails a violation of fat metabolism

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The presence of a mental illness increases the risk of an individual developing an addiction to substances, as noted in the chapter THE NEUROBIOLOGY OF SUBSTANCE USE, MISUSE, AND ADDICTION from the 2016 SAMHSA publication titled Facing Addiction in America: The Surgeon Generals Report on Alcohol, Drugs, and Health [Internet]