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3 Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, Peoples Republic of China *These authors contributed equally to this work Correspondence: Longtao Jin Women and Children Health Hospital of Zhenjiang, 20 Zhengdong Road, Zhenjiang, Jiangsu 212001, Peoples Republic of China Email [email protected] Zhao feng Liang Jiangsu Key Laboratory of Medical Science and Laboratory Medicine, School of Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, Peoples Republic of China Email [email protected] Abstract: Lung cancer is one of the most common causes of cancer-related deaths worldwide

Smoking is linked to numerous chronic pain symptoms and diseases

Through restricted blood flow, oxidative stress, DNA damage, and hormonal imbalance

They say their findings also align with theories that the brains reward system is implicated in the use of multiple substances