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On the other hand, short-nosed breeds of dogs (such as Bulldogs and Pugs) have higher rates of lung cancer, since inhaled smoke particles have less of a chance to become trapped in their nasal passages, and instead go directly to their lungs

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If a patient does not respond to varenicline, combining it with a nicotine patch can enhance its efficacy, as was shown in a long-term randomized controlled trial (Chang PH et al, BMC Public Health 2015;15:689)

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