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There are anatomic differences in the lung that persist for years after smokers quit and gene activity also remains altered. Light Smokers and COPD Smokings effect on lung function explains why smokers are more likely to develop chronic obstructive pulmonary disease (COPD), which is diagnosed when lung function dips below a certain threshold

After a smoker quits smoking for 10 years, his risk of lung cancer will be reduced by 30% to 50% compared to those who continue to smoke

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However, even in these scenarios, it is still rare for the levels to reach the threshold that would cause a positive test result