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In this study, compared with gradual nicotine reduction, immediate reduction was associated with lower toxicant exposure across time, smoking fewer CPD (cigarettes per day), greater reduction in dependence, and more cigarette-free days

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1, page 25 January 1948 How mild can a cigarette be? Camel advertisement Modern Medicine, page 117 April 15, 1949 Heres what throat specialists reported Camel advertisement Journal of the American Medical Association, vol