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However, there is currently no statistically significant evidence that NPs increase rates of smoking cessation compared with other products or control. To view or add a comment, sign in USA: GLP-1s Hold Promise as Treatment for Tobacco/Nicotine Use Disorder "Recent clinical data, including both quasi-experimental studies and randomized controlled trials, have supported the use of GLP-1 receptor agonists in reducing tobacco or nicotine use, particularly among those with concomitant diabetes mellitus type II (DM2).15 A recent cross-sectional, survey-based pilot study examined cigarette smoking among individuals with DM2 after initiation of GLP-1 receptor agonist therapy.16 A total of 48 individuals completed the survey, which assessed cigarette smoking and associated cravings with the Fagerstrm Test for Nicotine Dependence