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If you smoke even a little bit youll erode the genetic material of most of the cells in your body. Researchers compared 2,490 tissue samples from tobacco smokers and 1,063 from non-smokers to examine the mutational consequences of smoking

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In a randomized crossover trial comparing healthy subjects who smoked tobacco (maximum of 10 cigarettes per month), the acute use of nicotine-containing e-cigarettes significantly increased levels of circulating endothelial progenitor cells (flow cytometry) to the same magnitude as after smoking a traditional cigarette (41)