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Patients who cannot tolerate PPIs or require alternative options may use histamine 2-receptor antagonists H2RAs such as Famotidine or Nizatidine (Ranitidine is no longer recommended due to withdrawal from many markets), which work by inhibiting histamine-induced acid secretion

By spreading the tobacco on the device and adding a rolling paper, the user can close the roller and either turn a wheel or slide a mechanism

Corded or Cordless

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