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Young adults with cancer are already at increased risk for adverse outcomes after their cancer, including second cancers, so reducing exposure to harmful chemicals, such as those in e-cigarettes, is an important strategy to reduce their risk. Use of e-cigarettes has increased dramatically among young adults compared with other age groups

Fetal programming refers specifically to in utero processes that shape disease susceptibility, whereas developmental reprogramming encompasses broader mechanisms, including epigenetic modifications such as DNA methylation, which may occur throughout early development

Smokers damage not only their own health, but also the health of those who surround them

Observational studies show associations between tobacco use and increased rates of non-alcoholic fatty liver disease, but more research specific to smokeless tobacco is needed to fully characterise this relationship