pipe tobacco humidor 0076:: 1920s Briggs wood, barrel form Vintage Italian brown leather wrapped

It differs from moist snuff or chewing tobacco in that it is made from steam-cured tobacco leaves, rather than fire-cured ones, and its health effects are markedly different, with epidemiological studies showing lower rates of cancer and other tobacco-related health problems than cigarettes, American "chewing tobacco", Indian gutka or African-type tobacco products

Symptoms begin to develop when the bodys oxygen demand increases and different symptoms may develop depending on which artery is narrowed: Unusual heartbeat and arrhythmia, Heart palpitations Pain or pressure in the upper body, such as the chest, arms, neck and jaw (this condition is commonly known as angina), Difficulty breathing, shortness of breath

J Pharmacol Exp Ther (1997) 280:111736

Most of the larger contributions came from medical professionals