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Once frozen, the tobacco can become brittle, and any trapped moisture might mess with the overall burn

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Following the deterministic United States National Research Council/ Environmental Protection Agencys risk assessment frameworkwhich consists of four key steps: hazard identification, dose-response assessment, exposure assessment and risk characterizationPokhrels team estimated systemic risks using a Hazard Quotient (HQ) approach upon exposure to diacetyl among teens and adults who use e-cigarettes