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They include: Relaxation of the upper airway muscles caused by nicotine Increased upper airway inflammation Changes in sleep patterns (increased sleep deprivation, sleep fragmentation, etc.) More frequent sleep arousal caused by nicotine Research suggests that smoking can disrupt healthy sleep patterns

Juul e-liquids sold in the US and Canada contain up to 59 mg of nicotine per mL, comprising about 5% of the liquid, but EU regulations limit nicotine content to approximately a third of that amount at 20 mg/mL, about 1.7%, which the company adhered to, based on our results

Even infrequent exposure to carcinogens and toxicants contributes to cumulative damage over time