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That leaves the door open for unexpected interactions with other substances

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What's new is that state and local levies have grown so onerous in some parts of the country that they almost could be called "prohibition by price." And like other forms of prohibition, this one has led to a spike in smuggling-related criminal activity as smokers turn to illicit distribution channels

One of the implications [of this study] is we need to really get people to understand that quitting cold turkey is more effective, it kind of gets it over with, Eriksen said