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Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

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The principal targets of indirect regulation are antioxidant signaling molecules (Nrf2, PPAR, PRDX2, and so on), anti-inflammatory signaling molecules/pathways (NR4A1, p38 MAPK pathway, and NF-B pathway, and so on) and anti-fibrosis signaling molecules/pathways (YAP pathway, and so on)

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